2020 – Duke Global Health Innovation Center

18Dec 2020 by Melissa Slogan

TRACKING COVID VACCINE REGULATORY APPROVALS AROUND THE WORLD

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WEEKLY COVID VACCINE RESEARCH UPDATE FRIDAY, DECEMBER 18, 2020 Data Updates High-income country confirmed dose total: 4 billion Upper-middle-income country total: 1.1 billion Lower-middle-income country total: 1.8 billion Low-income country total: 0 COVAX total: 870 million Total worldwide confirmed purchases of Covid-19 vaccines: 7.7 billion doses Weekly Insights and Interesting Trends Author: Andrea Taylor Tracking regulatory approvals around the world We have seen a lot of movement in regulatory approval of Covid-19 vaccines over the past two weeks, as vaccination campaigns begin to roll out. When tracking the Covid-19 vaccine landscape, it is important to keep in mind the difference between emergency use authorization and full authorization. Most Covid-19 vaccine approvals received thus far have been limited to emergency use. This may be granted to address a health emergency, on…

14Dec 2020 by Melissa Slogan

WHAT ARE THE LATEST DEVELOPMENTS WITH VACCINES DEVELOPED IN RUSSIA AND CHINA?

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WEEKLY COVID VACCINE RESEARCH UPDATE MONDAY, DECEMBER 14, 2020 Data Updates High-income country confirmed dose total: 3.9 billion Upper-middle-income country total: 1 billion Lower-middle-income country total: 1.8 billion Low-income country total: 0 COVAX total: 700 million Total worldwide confirmed purchases of Covid-19 vaccines: 7.4 billion doses Weekly Insights and Interesting Trends Author: Andrea Taylor What are the latest developments with vaccines developed in Russia and China? We are frequently asked why some data about vaccines purchased by Russia and China appear to be missing from our data. The answer is because both countries control largely state-owned vaccine development and manufacturing chains, and, in part because of this, are notably less transparent than some other countries about advance purchases for domestic use as well as exports. Our dataset includes publicly announced…

02Nov 2020 by kmitch@duke.edu

Press Release: New Study Shows Rich Country Shopping Spree for COVID-19 Vaccines Could Mean Fewer Vaccinations for Billions in Low-Income Countries

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Data reveal members of a global pact promising vaccine equity are among those undermining the initiative; frenzy of deals covers some 8.8 billion doses Durham, NC, USA (November 2, 2020)—A new global assessment of purchasing agreements for COVID-19 vaccines reveals that high-income countries, as well as a few middle-income countries flush with manufacturing capacity, have already purchased nearly 3.8 billion doses, with options for another five billion. The analysis, released today by the Duke Global Health Innovation Center, shows that many of these countries will be able to vaccinate their entire populations—and some many times over—before billions of people are vaccinated in low-income countries. “An ambitious effort to create a global system of vaccine equity is being undermined as a handful of countries—including those who made a commitment to equality—secure…

20Aug 2020 by Jane Shealy

World Mosquito Day 2020

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Today, we observe World Mosquito Day to commemorate British doctor Sir Ronald Ross's discovery in 1897 that female mosquitoes transmit malaria. Malaria is a serious disease transmitted to humans through mosquitos. It causes fever, chills, and other flu-like symptoms. If left untreated, it can be life-threatening. In 2018, there were an estimated 228 million cases of malaria and 405,000 deaths worldwide. World Mosquito Day 2020 aims to raise awareness about the causes of malaria, its symptoms, and effective interventions. One of the most effective malaria-prevention interventions in high-burden countries is to sleep under a long-lasting insecticide-treated bed net, designed to physically block and kill mosquitoes. In 2007, the WHO recommended that all countries purchase and provide LLINs to their people at no or low cost. Even with significant financial backing from governments and international…

19Aug 2020 by Jane Shealy

GHIC Colleagues Lead Bass Connections Projects

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The Duke Global Health Innovation Center in cooperation with Bass Connections is giving Duke University students the chance to tackle complex problems throughout the world. The program—named in honor of donors Anne T. and Robert M. Bass—exemplifies Duke University’s commitment to integrating research, education, and civic engagement. This year, two GHIC colleagues—Andrea Thoumi and Diana Silimperi—will direct research teams in applying classroom training and an entrepreneurial spirit to solve pressing local problems with global application. Community-based Testing and Primary Care to Mitigate COVID-19 Transmission COVID-19 has exposed a need for rapid, accessible testing and clinical assessment in vulnerable populations, along with effective care that reaches communities in the longer-term. In Durham County, Black and Latinx communities are bearing disproportionate COVID-19 morbidity and mortality. The roots of health disparities are complex…

27Jul 2020 by Jessica Harris

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Every Second Matters for Mothers and BabiesTM—Uterine Balloon Tamponade (ESM-UBT) Every year, an estimated 130,000 women die from postpartum hemorrhage—uncontrolled blood loss from mothers during birth. This case study – the first in a series from the Launch and Scale Speedometer initiative – presents an overview of key elements that determined the pace of introduction and uptake of the ‘Every Second Matters for Mothers and BabiesTM-Uterine Balloon Tamponade’ to treat postpartum hemorrhage. This simple and inexpensive life-saving intervention, fashioned from a condom attached to a Foley catheter, was designed for use in low-resource settings. Read more about it here.

20Jul 2020 by Jane Shealy

The Future of Maternal, Newborn, and Child Health Innovation: Digital Forum Co-Hosted by Duke University and SL@B

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Join us on Wednesday, July 22, 8 am EDT, for The Future of Maternal, Newborn, and Child Health Innovation, co-hosted by Duke University and SL@B. Registration available HERE. Despite significant progress globally, persistent challenges in maternal, newborn, and child health continue to exist. Many solutions have emerged, ranging from evidence-based implementation programs to novel solutions that leapfrog conventional approaches. This forum brings together leaders from the public and private sectors, innovators, and researchers to present insights from the Saving Lives at Birth (SL@B) program, including findings from the recent program evaluation, and to discuss the path forward for MNCH innovation in the next decade. Topics include: What are the implications of the SL@B program evaluation? How can the MNCH funding and innovation community better respond to and address current challenges…

16Jul 2020 by Jane Shealy

Partnerships for Impact: The SL@B Approach to Fostering Connections

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By Sowmya Rajan Creating a lasting impact that addresses complex global health challenges needs more than a game-changing innovation. Strong partnerships are needed at every stage of the innovation’s growth trajectory, from ideation, to implementation and scale. Some of these partnerships, established at the right time with the right stakeholders, can transform the innovation’s development and its pathway to scale. But what are the crucial partnerships that innovators need, and how can funders support innovators in establishing such partnerships? The Saving Lives at Birth (SL@B) program, a partnership of global health funders aimed at reducing maternal and infant mortality, provided funding to grantees and strategic connections. Through the Evaluation of SL@B (ESL@B) program, we examine how the program fostered partnerships and offered technical support to address innovators’ most critical needs…

10Jul 2020 by Jane Shealy

Developing Human Capital in Response to Maternal and Newborn Child Healthcare Needs

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Continuous innovation in the Maternal and Newborn Child Health sector plays a crucial role in reducing maternal and neonatal mortality. As new products and services continuously crop up in this space, human capital becomes key in implementing and scaling these innovations. However, setting up human capital structures is a challenge, especially in new organizations focused on the development of an innovation and perhaps only hiring for technical skills needed to develop the innovation. Human capital structures become increasingly critical as organizations attempt to hire and retain the right individuals, then motivate, reward, and compensate top talent. The Accelerating Saving Lives at Birth program recognized the important role that human capital plays in the launch and scale of innovations and developed a set of best practices outlined in the ‘team’ domain under the Framing…

06Jul 2020 by Jane Shealy

Accelerating Impact: How Funders and Other Partners can Speed the Pathway to Scale

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By Andrea Taylor For social innovations, scaling is the key to impact. But how do these innovations scale, and how can funders, accelerators, and other partners accelerate that process? We took a close look at the experience of a sample of innovators funded by the Saving Lives at Birth program to answer this question. Their journeys provide insight into which factors are most helpful on the pathway to scale and how funders and other partners can support and speed up this process. Through semi-structured interviews with eleven innovator organizations, we learned that there are three key factors that accelerate the path to scaling: Preparation for scale at the early stages of innovation development. For some innovators, the funding application process served as a forcing mechanism to prompt early thinking about…