Regions
- Africa
Countries
- Kenya
- Senegal
- South Africa
ALIGN Consortium
Project overview
Advancing Country-Led Innovation Introduction through Government Engagement and EvideNce
The ALIGN Consortium aims to improve health outcomes by strengthening the critical decision-making systems that determine how health product innovations are prioritized and introduced in countries, to make those systems more effective and efficient. Comprised of the Duke Global Health Innovation Center, the South African Medical Research Council (SAMRC), Keprecon, and ENDA Santé, the ALIGN Consortium supports the national governments in Kenya, Senegal, and South Africa to enhance innovation introduction, looking at four focus areas: whole-of-government coordination and capacity strengthening, data-driven decision-making, whole-of-market engagement (including national, regional, and global engagement), and portfolio-based planning. The goal is to create more accountable, resilient health systems that deliver better health outcomes faster for all, and to generate insights, tools, and resources that can be used by stakeholders around the world.
Check out ALIGN’s shared resource for better health product decision-making.
ALIGN Global Market Intelligence Hub
ALIGN Global Market Intelligence Hub
Eager to learn more?
- We’ve launched a newsletter, The Compass. Each issue will share evidence, experiences, lessons, and updates from across the Consortium and beyond. Our first issue (July 2026) is out. Subscribe to receive future issues!
- We published a case study series as part of our shared learning agenda—featuring Thailand, the Netherlands, and Ghana. In each piece, authors examine the persistent challenge of introducing new health innovations, looking at how each country evaluates, prioritizes, finances, and sustains innovations within real fiscal and political constraints (July 2026).
- Check out our white paper on the ALIGN Global Market Intelligence Hub (April 2026).
- Read our Open Letter: Building Stronger Systems for Health Innovation Introduction (February 2026), calling for urgent reforms to strengthen national systems for health innovation introduction through four pillars: (1) whole-of-government coordination and capacity; (2) improved data availability and use; (3) multi-sector engagement for alignment and accountability; and (4) portfolio-based prioritization and planning.
- Visit the ALIGN Exchange Substack for frequent posts that capture insights from ALIGN Consortium members on our work.
Topics
- Access to Medicine / Health
- AI, Data, Digital Health
- Financing, Health Policy, Regulation, Universal Health Care
- Health Systems, Primary Care
Capabilities
- Capacity Building and Education
- Convening
- Evaluating projects, programs, and portfolios
- Evidence generation through research
- Sourcing and scaling health innovations
Funders/Sponsors
Gates Foundation
Partners
Duke University; Keprecon; ENDA Sante; SAMRC
Related resources
The ALIGN Coalition. "The ALIGN Market Intelligence Hub: a Shared Resource for Better Health Product Decision-making." April 29, 2026. (White paper, PDF)
ALIGN Consortium. (2026, March 19). From fragmentation to foresight. Substack. https://open.substack.com/pub/alignconsortium/p/part-5-applying-a-portfolio-based?utm_campaign=post-expanded-share&utm_medium=web
An Open Letter: Building Stronger Systems for Health Innovation Introduction
The accelerating pace of health innovation offers unprecedented opportunities to improve health outcomes globally, from long-acting HIV prevention to curative gene therapies and AI-enabled diagnostics. Yet, the gap between innovation potential and equitable delivery remains wide, particularly for low- and middle-income countries (LMICs) facing fiscal constraints, fragmented systems, and declining external aid. Evidence shows that the introduction phase—where countries prioritize, finance, and prepare for new technologies—is a critical bottleneck. Current processes are hindered by fragmented data, misaligned priorities, and weak coordination among stakeholders. This letter calls for urgent reforms to strengthen national systems for innovation introduction.
ALIGN Consortium. (2026, February 12). Part 4: Market intelligence is a crucial tool for decision-making. Substack. https://alignconsortium.substack.com/p/part-4-market-intelligence-is-a-crucial?r=6vxcfe&utm_campaign=post&utm_medium=web&triedRedirect=true
ALIGN Consortium. (2026, January 29). Part 3: The importance of “whole-of-market engagement”. Substack. https://alignconsortium.substack.com/p/part-3-the-importance-of-whole-of
ALIGN Consortium. (2026, January 15). Part 2: A closer look at the “whole-of-government coordination and capacity” pillar. Substack. https://alignconsortium.substack.com/p/part-2-a-closer-look-at-the-whole
ALIGN Consortium. (2025, December 12). Introducing ALIGN. Substack. https://open.substack.com/pub/alignconsortium/p/introducing-align?r=6vxcfe&utm_campaign=post&utm_medium=web
Related news
Wed Jul 15 2026 - 📄 Download the full Netherlands case study. (Also in this series: Ghana and Thailand.) Health leaders in all health systems must make critical decisions about which products―including diagnostics, medical devices, medicines, and vaccines―and services to provide… Read more
Wed Jul 15 2026 - 📄 Download the full Ghana case study. (Also in this series: Thailand and the Netherlands.) Health leaders in all health systems must make critical decisions about which products―including diagnostics, medical devices, medicines, and vaccines―and services… Read more
Wed Jul 15 2026 - 📄 Download the full Thailand case study. (Also in this series: Ghana and the Netherlands.) Health leaders in all health systems must make critical decisions about which products―including diagnostics, medical devices, medicines, and vaccines―and services to… Read more
Wed Apr 29 2026 - Health leaders, particularly those in low- and middle-income countries (LMICs), face a structural gap between the rapid pace of health innovation and the ability of their countries to anticipate, prioritize, finance, and introduce new products effectively… Read more
Wed Feb 18 2026 - In this open letter, members of the ALIGN Consortium call for urgent reforms to strengthen national systems for health innovation introduction through four pillars: (1) whole-of-government coordination and capacity; (2) improved data availability and use; (3)… Read more
Mon Dec 8 2025 - The ALIGN Consortium aims to improve health outcomes by strengthening the critical decision-making systems that determine how health product innovations are prioritized and introduced in countries, to make those systems more effective and efficient. Comprised… Read more
Sun Dec 7 2025 - Strengthening Health Innovation Introduction Policy, financing, and advocacy enablers of effective, efficient innovation introduction Health innovations hold immense promise for improving lives, especially in low- and middle-income countries (LMICs). Yet many of these innovations fail… Read more
Wed Oct 29 2025 - New Initiative Introducing The ALIGN Consortium Advancing Country-Led Innovation Introduction through Government Engagement and EvideNce Members of the ALIGN Consortium Executive Committee strategize on effective, efficient innovation introduction. Photo taken on August 19th, 2025, Nairobi… Read more